Periodic Labs

AI-first drug design built on AlphaFold for pharma R&D.

Isomorphic Labs is an AI-first drug discovery company spun out of Google DeepMind, building generative and predictive ML models for molecular design and drug-performance prediction. Its Drug Design Engine builds on AlphaFold to advance internal and partnered pipelines with Eli Lilly, Novartis, and J&J. It is a drug-discovery company that works through pharma R&D partnerships rather than a self-serve product.

Autonomous AI labs pursuing scientific superintelligence.

Lila Sciences is building a 'scientific superintelligence' platform that pairs a proprietary AI model with autonomous AI Science Factory lab instruments to generate hypotheses, design and run experiments, and learn in real time. It offers Catalyst, which augments existing R&D, and Creation, for new discoveries, across materials, therapeutics, chemicals, and energy. It is a platform and research company engaged through partnership rather than self-serve.

Frontier protein language models (the ESM family) for biology.

EvolutionaryScale builds frontier protein language models — the ESM family, including ESM3, which reasons jointly over sequence, structure, and function. ESM3-open ships open weights and code under a non-commercial license, while larger models are served via its Forge API and AWS/NVIDIA partnerships. It is both an open-model provider and an API platform for protein design and understanding.