CuspAI

AI scientists paired with autonomous labs to discover new materials.

Periodic Labs is building AI scientists and the autonomous laboratories for them to operate, automating hypothesis generation, experiments, and analysis across the physical sciences. Its initial targets include discovering higher-temperature superconductors and new materials for chipmakers. It is a research-stage company deploying with industry partners rather than a self-serve product.

Autonomous AI labs pursuing scientific superintelligence.

Lila Sciences is building a 'scientific superintelligence' platform that pairs a proprietary AI model with autonomous AI Science Factory lab instruments to generate hypotheses, design and run experiments, and learn in real time. It offers Catalyst, which augments existing R&D, and Creation, for new discoveries, across materials, therapeutics, chemicals, and energy. It is a platform and research company engaged through partnership rather than self-serve.

Generative protein language models that design novel proteins.

Profluent uses generative AI — its ProGen-lineage protein language models — to author novel proteins from scratch or from natural scaffolds, for medicine and agriculture. It released OpenCRISPR-1, described as the first AI-designed gene editor (open-licensed and published in Nature), and is expanding into antibodies and enzymes. It operates as an AI protein-design company working through partnerships with open-sequence releases, not a self-serve consumer platform.