Basecamp Research

Generative protein language models that design novel proteins.

Profluent uses generative AI — its ProGen-lineage protein language models — to author novel proteins from scratch or from natural scaffolds, for medicine and agriculture. It released OpenCRISPR-1, described as the first AI-designed gene editor (open-licensed and published in Nature), and is expanding into antibodies and enzymes. It operates as an AI protein-design company working through partnerships with open-sequence releases, not a self-serve consumer platform.

Foundation models for molecular structure and antibody design.

Chai Discovery builds foundation models for drug discovery — Chai-1 for biomolecular structure prediction across proteins, ligands, DNA/RNA, and glycans, and Chai-2 for de novo antibody design. Chai-1 weights and inference code are released for non-commercial use, and a free web server runs the model in-browser. It is both a model provider and a usable platform.

AI scientists paired with autonomous labs to discover new materials.

Periodic Labs is building AI scientists and the autonomous laboratories for them to operate, automating hypothesis generation, experiments, and analysis across the physical sciences. Its initial targets include discovering higher-temperature superconductors and new materials for chipmakers. It is a research-stage company deploying with industry partners rather than a self-serve product.