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Cradle vs Profluent

A side-by-side comparison of Cradle and Profluent, two Science tools, drawn from Ignaite's continuously-verified listings.

Compared from listings verified as of

Cradle

Science

AI protein-engineering platform for faster lab design rounds.

View Cradle

Profluent

Science

Generative protein language models that design novel proteins.

View Profluent

At a glance

Feature comparison of Cradle and Profluent
AttributeCradleProfluent
CategoryScienceScience
PricingPAIDPAID
LicenseProprietaryProprietary
DeploymentCloudCloud
PlatformsWebWeb
Model support
Vendor (differs)CradleProfluent Bio

The honest brief

Cradle

Self-serve web SaaS for protein engineering with per-customer models and an in-house wet lab — a usable product where most rivals are partnership-only.

  • Self-serve web platform
  • Multi-property optimization
  • Per-customer models on your lab data
  • Customers keep IP, no royalties
  • Enterprise sales-led pricing
  • No public free tier
  • Needs customer wet-lab data
  • Not a downloadable model

Profluent

Pairs frontier protein LLMs with openly released designs like OpenCRISPR-1, while most peers keep AI-designed molecules proprietary.

  • ProGen protein-LLM lineage
  • Open-released gene editor
  • Nature-published work
  • Eli Lilly and IDT partnerships
  • Partnership/licensing only
  • No self-serve platform
  • Open releases are sequences, not a service
  • Opaque pricing