Cradle vs Profluent
A side-by-side comparison of Cradle and Profluent, two Science tools, drawn from Ignaite's continuously-verified listings.
Compared from listings verified as of
At a glance
| Attribute | Cradle | Profluent |
|---|---|---|
| Category | Science | Science |
| Pricing | PAID | PAID |
| License | Proprietary | Proprietary |
| Deployment | Cloud | Cloud |
| Platforms | Web | Web |
| Model support | — | — |
| Vendor (differs) | Cradle | Profluent Bio |
| Capabilities (differs) |
|
|
The honest brief
Cradle
Self-serve web SaaS for protein engineering with per-customer models and an in-house wet lab — a usable product where most rivals are partnership-only.
- Self-serve web platform
- Multi-property optimization
- Per-customer models on your lab data
- Customers keep IP, no royalties
- Enterprise sales-led pricing
- No public free tier
- Needs customer wet-lab data
- Not a downloadable model
Profluent
Pairs frontier protein LLMs with openly released designs like OpenCRISPR-1, while most peers keep AI-designed molecules proprietary.
- ProGen protein-LLM lineage
- Open-released gene editor
- Nature-published work
- Eli Lilly and IDT partnerships
- Partnership/licensing only
- No self-serve platform
- Open releases are sequences, not a service
- Opaque pricing
When to pick which
Both cover Protein design.
Pick Cradle if you need Fine-tuning / training.
- Fine-tuning / training (secondary capability)
Pick Profluent if you need Antibody design and Molecular design.
- Antibody design (secondary capability)
- Molecular design (secondary capability)