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Chai Discovery vs Cradle

A side-by-side comparison of Chai Discovery and Cradle, two Science tools, drawn from Ignaite's continuously-verified listings.

Compared from listings verified as of

Chai Discovery

Science

Foundation models for molecular structure and antibody design.

View Chai Discovery

Cradle

Science

AI protein-engineering platform for faster lab design rounds.

View Cradle

At a glance

Feature comparison of Chai Discovery and Cradle
AttributeChai DiscoveryCradle
CategoryScienceScience
Pricing (differs)FREEMIUMPAID
License (differs)Open coreProprietary
DeploymentCloudCloud
Platforms (differs)Web, APIWeb
Model support——
Vendor (differs)Chai DiscoveryCradle

The honest brief

Chai Discovery

One of the few drug-discovery shops to ship open model weights plus a free in-browser server, rather than locking everything behind pharma partnerships.

  • Free in-browser structure prediction
  • Open Chai-1 weights
  • SOTA protein-ligand accuracy
  • OpenAI-backed
  • Weights non-commercial only
  • Chai-2 not open
  • Young company (2024)
  • Core IP still proprietary

Cradle

Self-serve web SaaS for protein engineering with per-customer models and an in-house wet lab — a usable product where most rivals are partnership-only.

  • Self-serve web platform
  • Multi-property optimization
  • Per-customer models on your lab data
  • Customers keep IP, no royalties
  • Enterprise sales-led pricing
  • No public free tier
  • Needs customer wet-lab data
  • Not a downloadable model
Chai Discovery detailsCradle detailsAll Science apps