Chai Discovery vs Cradle
A side-by-side comparison of Chai Discovery and Cradle, two Science tools, drawn from Ignaite's continuously-verified listings.
Compared from listings verified as of
Chai Discovery
ScienceFoundation models for molecular structure and antibody design.
View Chai DiscoveryAt a glance
| Attribute | Chai Discovery | Cradle |
|---|---|---|
| Category | Science | Science |
| Pricing (differs) | FREEMIUM | PAID |
| License (differs) | Open core | Proprietary |
| Deployment | Cloud | Cloud |
| Platforms (differs) | Web, API | Web |
| Model support | — | — |
| Vendor (differs) | Chai Discovery | Cradle |
| Capabilities (differs) |
|
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The honest brief
Chai Discovery
One of the few drug-discovery shops to ship open model weights plus a free in-browser server, rather than locking everything behind pharma partnerships.
- Free in-browser structure prediction
- Open Chai-1 weights
- SOTA protein-ligand accuracy
- OpenAI-backed
- Weights non-commercial only
- Chai-2 not open
- Young company (2024)
- Core IP still proprietary
Cradle
Self-serve web SaaS for protein engineering with per-customer models and an in-house wet lab — a usable product where most rivals are partnership-only.
- Self-serve web platform
- Multi-property optimization
- Per-customer models on your lab data
- Customers keep IP, no royalties
- Enterprise sales-led pricing
- No public free tier
- Needs customer wet-lab data
- Not a downloadable model
When to pick which
Both cover Protein design.
Pick Chai Discovery if you need Protein structure prediction and Antibody design.
- Protein structure prediction (primary capability)
- Antibody design (primary capability)
Pick Cradle if you need Fine-tuning / training.
- Fine-tuning / training (secondary capability)
Cradle leans on Protein design as a headline capability; Chai Discovery treats it as secondary.
- Protein design (primary capability)
They also differ on:
- Pricing
- FREEMIUM · PAID
- License
- Open core · Proprietary
- Platforms
- Web, API · Web