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Agno vs Mastra

A side-by-side comparison of Agno and Mastra, two Orchestration tools, drawn from Ignaite's continuously-verified listings.

Compared from listings verified as of

Agno

Orchestration

High-performance Python framework for multi-agent systems.

View Agno

Mastra

Orchestration

TypeScript framework for building AI agents and workflows.

View Mastra

At a glance

Feature comparison of Agno and Mastra
AttributeAgnoMastra
CategoryOrchestrationOrchestration
Pricing (differs)FREEFREEMIUM
License (differs)Open sourceOpen core
Deployment (differs)Hybrid
PlatformsAPI, CLIAPI, CLI
Model support (differs)Model-agnosticMulti-model
Vendor (differs)AgnoMastra

The honest brief

Agno

Built for speed and scale — agents instantiate near-instantly with low memory, and ship to production via the bundled AgentOS FastAPI runtime.

  • Fast agent instantiation, low memory use
  • Multi-modal agents and agent teams
  • Bundled AgentOS production runtime
  • Model- and provider-agnostic
  • Younger than LangChain and LlamaIndex
  • Rapid changes since the Phidata rename
  • Smaller community and ecosystem

Mastra

Built TypeScript-first on the Vercel AI SDK — far less boilerplate and faster runtime than LangGraph's abstractions.

  • TypeScript-native, low boilerplate
  • Graph workflow engine plus memory and tools
  • Self-hostable or deploy to Mastra Cloud
  • Built-in observability
  • Younger ecosystem, fewer examples
  • Small plugin set (~50-60 integrations)
  • Workflow chaining unintuitive for complex branching
  • TypeScript-only; no Python path